I’ve been to a number of different places for face treatments in California and really liked Fractional CO2 laser resurfacing I received with my dermatologist many years ago. I went in for a consultation at SMooth Solutions Medspa and met with the owner. I was very quickly impressed by her knowledge, not only of the treatments, but the underlying mechanics of the machines. We spoke about what I was looking for and she provided a treatment unique to my needs. I am about 1 week post-treatment and I can already see some improvements. To be fair tho, this stuff really takes multiple months to really see the benefits, but it is already noticeably better than when I had treatments at LaserAway.
WHAT IS MESOPEPTIDE?

YOUR MESOPEPTIDE TREATMENTS IN NAPERVILLE
Treatment information
Key Actives
- Palmitoyl tripeptide-5
- Acetyl tetrapeptide-9
- Hyaluronic acid
Best For
- Sagging
- Loss of jawline definition
- Thinning skin
Pairs With
- RF Microneedling
- Microneedling
- LaseMD Ultra
- PRÉIME DermaFacial
Downtime
No downtime beyond your paired treatment
YOUR PERSONALIZED MESOPEPTIDE RESULTS
Our peptide mesotherapy treatments follow a structured, medical-grade approach to rebuilding skin density and structural support. By targeting concerns at a deeper layer, results develop progressively and are tailored to your skin type, age, and goals.
JAWLINE REDEFINITION
Targeted peptide mesotherapy helps redefine a softening jawline and restore structural contours without the need for surgery or filler.
STRUCTURE AND DENSITY RESTORATION
Biomimetic peptides—palmitoyl tripeptide-5 and acetyl tetrapeptide-9—combine with hyaluronic acid to rebuild density and support in thin, aged skin.
IMPROVED SKIN FIRMNESS AND TIGHTENING
Delivered during RF microneedling, microneedling, LaseMD Ultra, or PRÉIME DermaFacial appointments, the treatment improves skin elasticity and firmness, reducing sagging and creating a visibly firmer result over time.
PROGRESSIVE REJUVENATION
As treatments continue, firmness builds gradually over a course of sessions as the peptides support the skin’s structure.
BRIGHTER, HEALTHIER-LOOKING SKIN
With no downtime beyond your paired treatment, your complexion benefits from enhanced structural support and cellular renewal.
LONG-TERM MAINTENANCE AND PREVENTION
Maintaining your results requires consistency. With a personalized maintenance plan and proper skincare, you can preserve your structural improvements and continue supporting skin health over time.

SCHEDULE YOUR MESOPEPTIDE APPOINTMENT IN NAPERVILLE
1867 Bay Scott Circle Suite 111 Naperville IL 60540
(630) 381-8952
CONTINUED IMPROVEMENT WITH MESOPEPTIDE TREATMENTS
- Progressive Rejuvenation: Biomimetic peptides and hyaluronic acid support the skin’s structure, helping firmness build gradually over a course of sessions.
- Improved Skin Quality: As treatments continue, thin and aging skin becomes smoother, firmer, and more resilient.
- Brighter, Clearer Complexion: Enhanced structural support and cellular renewal reveal a more radiant, youthful appearance.
- Smoother Texture: Targeted peptide mesotherapy refines texture and improves overall skin feel along a softening jawline.
- Long-Term Maintenance Control: With proper skincare, sun protection, and a personalized maintenance plan, structural results can be preserved over time.
Significant improvements can be seen in skin density, structural support, and firmness, leading to a visibly firmer and more defined appearance.
Mesopeptide works where the skin needs structural rebuilding, delivered during RF microneedling, microneedling, LaseMD Ultra, or PRÉIME DermaFacial appointments. Rather than adding volume like a dermal filler, this booster targets the deeper layers to rebuild density and support.
As your treatment plan progresses, you will notice gradual yet consistent improvements. With ongoing care and maintenance, results continue to build, helping you achieve a firmer, more redefined, and youthful-looking complexion.
OUR DIFFERENCE? MEDICAL PRECISION, STRUCTURED PROTOCOL, EVIDENCE-BASED PEPTIDE MESOTHERAPY
At SMooth Solutions Medspa, we focus on a science-driven approach to rebuilding skin density and structural support. Every treatment plan is built on clinical understanding, allowing you to make informed decisions about your skin and results.
While many treatments focus only on surface-level improvements, our approach delivers biomimetic peptides—palmitoyl tripeptide-5 and acetyl tetrapeptide-9—combined with hyaluronic acid to rebuild density and structure in thin, aged skin and a softening jawline. This ensures more effective, balanced, and structurally supported outcomes.
Through expert assessment, customized treatment planning, and structured follow-up care, we help you achieve visible improvements that continue over time. Our goal is not just short-term rejuvenation but long-term skin health, confidence, and natural structural support.
Frequently Asked Questions
Can Mesopeptide replace filler?
It works differently — Mesopeptide supports the skin's own density and structure rather than adding volume the way filler does. Your provider can tell you which approach, or combination, fits your goals.
How is this different from Mesotox?
Mesotox targets the micro-contractions behind expression lines; Mesopeptide targets skin density and structure, particularly along the jawline. Many patients use both.
How many sessions will I need?
Firmness builds gradually. Your provider will recommend a schedule based on your skin's starting point and goals.
Does this add downtime?
No — it's added within your existing treatment window and doesn't change your recovery.
What should I pair it with?
RF Microneedling and Microneedling are the most common pairings for jawline and density concerns, though your provider may recommend LaseMD Ultra or PRÉIME DermaFacial.

Combinable Treatments
Mesopeptide treatments can be combined with other advanced procedures to enhance results, improve skin density, and support long-term rejuvenation. Treatments such as RF microneedling, microneedling, LaseMD Ultra, and PRÉIME DermaFacial work together to allow the biomimetic peptides and hyaluronic acid to reach the deeper layers of skin where structural support needs to be rebuilt. When combined strategically, these treatments can enhance absorption of active ingredients, accelerate skin renewal, and deliver more noticeable and longer-lasting results. A customized combination approach allows us to target multiple concerns at once, including sagging, loss of jawline definition, and thinning skin.
Our personalized treatment plans may also include bundled options designed to maximize value and results. During your consultation, we will recommend the best combination based on your skin type, concerns, and long-term goals.

GET YOUR MESOPEPTIDE TREATMENT NOW
Restore a smoother, firmer, and more structured appearance with our advanced peptide mesotherapy treatments. From delivering biomimetic peptides—palmitoyl tripeptide-5 and acetyl tetrapeptide-9—combined with hyaluronic acid directly into the deeper skin layers to rebuild density in thin, aged skin and a softening jawline, we create personalized plans to target your unique concerns and deliver natural-looking results.
Visit our clinic for a professional skin evaluation or choose a virtual consultation to get started from the comfort of your home.
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Prioritize your self-care and unlock year-round benefits with the SMooth Solutions Membership Program. This exclusive opportunity allows you to enjoy substantial savings on skin care and explore the best products, treatments and services we have to offer at one convenient monthly cost. We provide flexible membership programs for anti-aging treatments and laser hair removal, so you can pick the package that meets your needs. Sign up today to get started!
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