I’ve been to a number of different places for face treatments in California and really liked Fractional CO2 laser resurfacing I received with my dermatologist many years ago. I went in for a consultation at SMooth Solutions Medspa and met with the owner. I was very quickly impressed by her knowledge, not only of the treatments, but the underlying mechanics of the machines. We spoke about what I was looking for and she provided a treatment unique to my needs. I am about 1 week post-treatment and I can already see some improvements. To be fair tho, this stuff really takes multiple months to really see the benefits, but it is already noticeably better than when I had treatments at LaserAway.
WHAT IS MESOTOX?

YOUR MESOTOX TREATMENT INFORMATION IN NAPERVILLE
Treatment information
Key Actives
- Acetyl hexapeptide-8
- Pentapeptide-18
- Niacinamide
Best For
- Dynamic wrinkles
- Forehead and frown lines
- Crow’s feet
Pairs With
- Microneedling
- RF Microneedling
- LaseMD Ultra
- Laser Genesis
Downtime
- Minimal downtime
- Any redness typically resolves within hours
Results
- Initial softening in 3 to 5 days
- Building to full effect around 2 weeks
YOUR PERSONALIZED MESOTOX RESULTS
Our treatments follow a structured, medical-grade approach to softening expression lines and refining skin quality without an injection into muscle. By delivering acetyl hexapeptide-8, pentapeptide-18, and niacinamide directly into the surface of the skin during a microneedling, RF microneedling, LaseMD Ultra, or Laser Genesis appointment, results develop progressively and are tailored to your skin type, age, and goals.
EXPRESSION LINE SOFTENING
Targeted mesotherapy boosters calm the micro-contractions responsible for forehead lines, frown lines, and crow’s feet, producing a softer, more relaxed finish.
DIRECT SKIN-LEVEL DELIVERY
Unlike traditional Botox injected into the muscle, Mesotox works directly at the skin level to extend your look between appointments or provide a gentler entry point.
IMPROVED SKIN TEXTURE
Combining peptides and niacinamide with advanced resurfacing treatments helps refine the skin’s surface and smooth dynamic wrinkles.
PROGRESSIVE REJUVENATION
Initial softening is typically seen in 3 to 5 days, building to full effect around 2 weeks over a course of sessions.
GENTLE ALTERNATIVE OR BOOSTER
Provides a refined option for patients who want to refresh their appearance without a full neuromodulator injection into muscle.
LONG-TERM MAINTENANCE
Expression line management is an ongoing process, and maintaining results requires consistency with a personalized schedule recommended by your provider.

SCHEDULE YOUR MESOTOX TREATMENT WITH US IN NAPERVILLE
1867 Bay Scott Circle Suite 111 Naperville IL 60540
(630) 381-8952
CONTINUED IMPROVEMENT WITH MESOTOX
- Progressive Rejuvenation: Mesotherapy-based peptides are delivered directly into the surface of the skin during your appointment to help expression lines improve gradually over time.
- Improved Skin Quality: As treatment sessions continue, skin becomes smoother and more refined.
- Brighter, Clearer Complexion: Reduction in micro-contractions and dynamic wrinkles reveals a softer, more youthful appearance.
- Smoother Texture: Direct delivery alongside microneedling or laser appointments helps address forehead lines, frown lines, and crow’s feet.
- Long-Term Maintenance Control: With proper skincare and a series of sessions, results can be built and maintained over time.
Significant improvements can be seen in expression lines, micro-contractions, and skin texture, leading to a more soft, relaxed, and refreshed complexion.
Mesotox acts as a specialized booster, delivered directly into the surface of the skin during your treatment rather than through an injection into the muscle. Rather than acting as a full neuromodulator, this booster provides a softer, more relaxed finish to dynamic lines.
As your treatment plan progresses, you will notice gradual yet consistent improvements. With ongoing care and maintenance sessions, results continue to build, helping you achieve a smoother and more refreshed appearance.
OUR DIFFERENCE? MEDICAL PRECISION, STRUCTURED PROTOCOL, EVIDENCE-BASED MESOTOX
At SMooth Solutions Medspa, we focus on a science-driven approach to expression-line management. Every treatment plan is built on clinical understanding, allowing you to make informed decisions about your skin and results.
While many treatments focus only on surface-level improvements or require deep muscle injections, our approach delivers acetyl hexapeptide-8, pentapeptide-18, and niacinamide directly into the surface of the skin during your microneedling, RF microneedling, LaseMD Ultra, or Laser Genesis appointment. This calms the micro-contractions responsible for forehead lines, frown lines, and crow’s feet for more effective, balanced, and natural-looking outcomes.
Through expert assessment, customized treatment planning, and structured follow-up care, we help you achieve visible improvements that continue over time. Our goal is not just short-term results but long-term skin health, confidence, and natural rejuvenation.
Frequently Asked Questions
Is Mesotox the same as Botox?
No — Mesotox uses very dilute peptides delivered into the surface of the skin to relax the look of expression lines, while Botox is injected into the muscle itself to block the nerve signal that causes it to contract.
Can I get Mesotox and Botox together?
Many patients use Mesotox to soften new lines between Botox appointments, though your provider will advise on timing based on your history.
How long do results last?
Results build over a course of sessions and are not permanent. Your provider will recommend a maintenance schedule at consultation.
Does Mesotox hurt?
The micro-injections are well tolerated by most patients; the treatment is roughly 30 minutes.
What can I pair Mesotox with?
Mesotox is commonly added to microneedling, RF microneedling, LaseMD Ultra, and Laser Genesis appointments.

Combinable Treatments
Mesotox treatments can be combined with other advanced skincare procedures to enhance results, improve skin quality, and support long-term rejuvenation. Treatments such as microneedling, RF microneedling, LaseMD Ultra, and Laser Genesis work together to deliver the peptides directly into the surface of the skin. When combined strategically, these treatments can enhance absorption of active ingredients, accelerate skin renewal, and deliver more noticeable and longer-lasting results. A customized combination approach allows us to target multiple concerns at once, including dynamic wrinkles, forehead and frown lines, and crow’s feet.
Our personalized treatment plans may also include bundled options designed to maximize value and results. During your consultation, we will recommend the best combination based on your skin type, concerns, and long-term goals.

GET YOUR MESOTOX TREATMENT NOW
Restore a softer, more relaxed finish with our advanced Mesotox treatments. By delivering peptides directly into the surface of the skin during a microneedling, RF microneedling, LaseMD Ultra, or Laser Genesis appointment rather than injecting into muscle, we create personalized plans to target your unique expression lines and deliver natural-looking results.
Visit our clinic for a professional skin evaluation or choose a virtual consultation to get started from the comfort of your home.
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Prioritize your self-care and unlock year-round benefits with the SMooth Solutions Membership Program. This exclusive opportunity allows you to enjoy substantial savings on skin care and explore the best products, treatments and services we have to offer at one convenient monthly cost. We provide flexible membership programs for anti-aging treatments and laser hair removal, so you can pick the package that meets your needs. Sign up today to get started!
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